Preoperative Radiotherapy as Adjuvant Treatment in Rectal Cancer
نویسندگان
چکیده
منابع مشابه
multimodal treatment of rectal cancer – eValuation of preoperatiVe radiotherapy
Colorectal cancer constitutes 10% of all malignant neoplasms and is the fourth most common cancer in men and the third most common cancer in women, worldwide (second most common in Poland). Unfortunately, despite large scale screening programs, changes in diet and lifestyle, colorectal cancer incidence rates for both male and female patients has increased. the aim of the study was to analyze th...
متن کاملPathology of rectal adenocarcinoma following preoperative adjuvant radiotherapy and chemotherapy.
The study group comprised 13 patients (mean age 68 years) with clinically fixed and biopsy proven moderately differentiated rectal adenocarcinoma (8 high rectal, 5 low-mid rectal) who received synchronous courses of preoperative combination chemotherapy and pelvic radiotherapy (radiotherapy alone in 3 cases) over a period of 8-20 weeks prior to surgical resection. All cases showed varying degre...
متن کاملA phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
PURPOSE To determine the maximum tolerated dose and the dose-limiting toxicity of capecitabine with standard radiotherapy (RT) as adjuvant treatment in patients with rectal cancer. METHODS AND MATERIALS Patients with Stage II/III rectal cancer after surgery were eligible. Total RT dose was delivered as DT 50 Gy in fractions of 2.0 Gy/day for 5 weeks to the pelvic area. Capecitabine was admini...
متن کاملAdjuvant Treatment for Rectal Cancer
Various approaches have been devised to improve the treatment outcomes of rectal cancer. These include new surgical methods5 and use of adjuvant treatment. However, there are lots of controversies concerning the extent of the surgery and the use of adjuvant treatment for different surgical approaches. In this article, we shall focus on the use of adjuvant treatment especially its integration wi...
متن کاملRemodelling of Extracellular Matrix in Rectal Cancer and Preoperative Radiotherapy
BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) remodelling enzymes and growth factors after radiotherapy and also their possible use as surrogate markers for complications. A secondary aim was to explore the use of these enzymes...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1988
ISSN: 0003-4932
DOI: 10.1097/00000658-198811000-00011